Gene Expression Data Show Direct Impact on the Core Biology of IPF ...
Scientists found that combining oxytocin with an Alk5 inhibitor revitalized extremely old male mice, boosting their lifespan and strength. Female mice showed only short-term improvements, highlighting ...
We're going to get started. Thank you, everyone, for joining us here in Berlin, and there are many more of you that are online. Welcome to the solid tumor update that we're having at ESMO 2025. We're ...
Researchers at Children's Hospital Los Angeles have discovered a key difference between the two main types of rhabdomyosarcoma—paving the way for more targeted treatments. The study, led by JinSeok ...
MMP14 as a central mediator of TGF-β1−induced extracellular matrix remodeling in graves’ orbitopathy
Department of Ophthalmology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory for the Prevention and Treatment of Major Blinding Eye Diseases, Chongqing, China ...
The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...
Heme oxygenase 1 (HO-1) has an influential yet insufficiently investigated effect on Sirtuin 1 (SIRT1), a histone deacetylase activated by nicotinamide adenine dinucleotide, which may impact the ...
Marfan syndrome (MFS) is a heritable connective tissue disorder caused by mutations in the Fibrillin‐1 gene, which encodes the extracellular matrix protein fibrillin‐1. Patients with MFS are ...
Type 2 diabetes mellitus–related sarcopenia (T2DMRS) is a common complication in elderly and advanced diabetes patients that affects long-term prognosis and quality of life. Skeletal muscle is the ...
One of the best ways to defeat cancer is by rousing the immune system to attack it. Experts have thought that immune cells had to be inside of tumors for one type of immunotherapy, known as checkpoint ...
Joanne Murphy-Ullrich, Ph.D., Professor Emerita, Molecular and Cellular Pathology, has been inducted into UAB's chapter of the National Academy of Inventors. Murphy-Ullrich was recognized at an ...
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