Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

The study systematically revealed that gut microbial genetic variations at the single-nucleotide resolution influence host cognitive exploratory behavior by regulating metabolites. The study further ...

The researchers used Merino sheep as an animal model, systematically collecting samples of their hindgut and ruminal microbiota, plasma metabolites, and neurocognitive behavioral phenotype data. Based ...

Summary: In a groundbreaking study using Merino sheep, researchers uncovered that tiny genetic variations within gut microbes can influence brain-related behavior. By sequencing over 5,000 microbial ...

Abstract: High-performance prediction of prostate cancer metastasis based on single nucleotide variations remains a challenge. Therefore, we developed a novel biologically informed deep learning ...

Department of Systems Biotechnology, Institute of Microbiomics, Chung-Ang University, Anseong, Republic of Korea The CRISPR-Cas system, an adaptive immune mechanism in prokaryotes against ...

Parasitic worms that infect humans are not interbreeding with those that infect cattle as previously thought. This is good news for when it comes to controlling schistosomiasis, a disease caused by ...