AZoLifeSciences on MSN

DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli

A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
eLife

Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...