“Traditional gene-expression microarray experiments offer a limited view of genome biology. To see the whole picture, a multidimensional approach is required that tests for gene expression, as well as ...

To map most of the genetic variation in the human genome, scientists need to look at several hundred thousand single nucleotide polymorphisms (SNPs) per individual. Most genotyping assays employ ...

Microarray technology has come of age as a powerful approach to revealing the genome and its dynamic expression through the application of gene-hybridization or gene-expression microarrays. While the ...

Take any two individuals, sequence and compare their genomic DNA, and you'll find that the vast majority (about 99.9%) of the sequences are identical. In the remaining 0.1% lie differences in disease ...

Numerous studies have shown that homologous recombination deficiency (HRD) is a genome-wide biomarker present in high grade ovarian and breast cancers. A cancer therapeutic class, PARP inhibitors, ...