A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about 0.01 mm in size, it must be tightly folded. DNA wraps around proteins call ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

Imagine if you could "print" a tiny skyscraper using DNA instead of steel. That’s what researchers at Columbia and Brookhaven are doing—constructing intricate 3D nanostructures by harnessing the ...

Not all DNA looks like the familiar double helix. Sometimes, parts of our genetic code fold into unusual shapes under certain conditions. One such structure known as a G-quadruplex (G4) looks like a ...